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Abstract Background Breast cancer is one of the most common diseases affecting women.Inherited susceptibility genes, BRCA1 and BRCA2, are considered in breast, ovarian and other common cancers etiology.BRCA1 and BRCA2 genes have been identified that confer a high degree of breast cancer risk.Objective Our study was performed to identify germline mu
The long distance export of livestock from Australia to Asia has long aroused controversy for suspected animal welfare concerns during and after the voyage.However, there is little or no information on the attitude of the Australian public towards this trade.A total of 522 Australians were surveyed in Brisbane to find out about their understanding
Each fall, monarch butterflies in eastern North America undergo an extraordinary long-distance migration to wintering areas in central Mexico, where they remain until returning northward in the spring.Migrants survive the overwintering period by metabolizing lipid reserves accumulated exclusively though floral nectar; however, there is little known
Abstract Cardiomyocyte pyroptosis and apoptosis play a vital role in the pathophysiology of several cardiovascular diseases.Our recent study revealed that gasdermin D (GSDMD) can promote myocardial I/R injury via the caspase-11/GSDMD pathway.We also found that GSDMD deletion attenuated myocardial I/R and MI here injury by reducing cardiomyocyte apo